“Some detailed targeting options have been removed: This ad group includes detailed targeting options that are either no longer available or unavailable when people are excluded from the audience...”

This error means that having Detailed Targeting Expansion (aka Advantage Detailed Targeting) on is not compatible with the objective you are choosing.

From time to time Meta introduces changes to the interests and other categories in the detailed targeting by deprecating some of them, as a result, the interests you were able to include/ exclude while creating an audience might not be supported by Meta API any longer.

You can either try selecting a different objective for the campaign or remove Detailed Targeting Expansion from the audience settings.

In case you need further help, please reach out to us via the chat bubble or email at support@bir.ch.